Therapeutic drug monitoring (TDM) advice

You can obtain advice on Therapeutic Drug Monitoring (TDM) from your ward pharmacist (via pager) or by contacting the Lady Cilento Children’s Hospital (LCCH) Pharmacy Department.

Paediatric TDM differs from that relating to adults, so please don’t hesitate to contact your Clinical pharmacist for advice regarding starting doses, or advice on interpreting blood levels and advice regarding appropriate dose adjustments.

Aminoglycosides

Gentamicin and Tobramycin

Note: Interpretation of the plasma drug levels require knowledge of patient’s condition, weight, height, serum creatinine, drug dose, exact time of commencement and end of infusion (including mode of administration) and exact times of blood collections.

Please contact the AMS Pharmacist for more information on training and support for clinicians who would like to utilise the AUC calculation tool.

Amikacin – Seek ID specialist/pharmacist advice on monitoring and appropriate target levels.

Glycopeptides

  • Vancomycin – therapeutic drug monitoring form
  • Teicoplanin – seek specialist ID/pharmacist advice on monitoring and appropriate target levels.

Antifungals

Antivirals

  • Ganciclovir and Valganciclovir – seek ID specialist/ pharmacist advice on monitoring and interpretation of levels.