Neonatal dosing
Specific neonatal antimicrobial dosing – Australasian Neonatal Medicines Formulary (ANMF)
| Antimicrobial | Link to recommended guideline/resource |
|---|---|
| Aciclovir IV | ANMF – Aciclovir monograph (2021) |
| Amikacin IV | ANMF – Amikacin monograph (2021) |
| Ampicillin IV | ANMF – Ampicillin monograph (2021) |
| Amoxicillin IV | ANMF – Amoxicillin monograph (2021) |
| Azithromycin IV | ANMF – Azithromycin monograph (2022) |
| Benzylpenicillin IV | ANMF – Benzylpenicillin monograph (2021) |
| Cefalexin PO | ANMF – Cefalexin monograph (2020) |
| Cefazolin IV | ANMF – Cefazolin monograph (2021) Comment: Does not provide CNS cover – seek ID advice |
| Cefotaxime IV | ANMF – Cefotaxime monograph (2020) |
| Ceftazidime IV | ANMF – Ceftazidime monograph (2022) |
| Clindamycin IV | ANMF – Clindamycin monograph (2022) Comment: Does not provide CNS cover – seek ID advice |
| Flucloxacillin IV | ANMF – Flucloxacillin monograph (2020) Comment: Higher oral mg/kg doses may be required in neonates – see AMH CDC for dosing recommendations |
| Gentamicin IV | ANMF – Gentamicin monograph (2021) Comment: TDM required. Seek AMS/ Paediatric pharmacist advice. |
| Meropenem IV | ANMF – Meropenem monograph (2021) |
| Metronidazole IV | ANMF – Metronidazole monograph (2020) |
| Piperacillin/ Tazobactam IV |
ANMF – Piperacillin/Tazobactam monograph (2020) Comment: Does not provide CNS cover – seek ID advice |
| Tobramycin IV | ANMF – Tobramycin monograph (2020) Comment: TDM required. Seek AMS/ Paediatric pharmacist advice. |
| Trimethoprim/ sulfamethoxazole PO |
ANMF – Trimethoprim/sulfamethoxazole monograph (2022) Caution: Kernicterus risk in neonates – seek ID advice |
| Vancomycin IV | ANMF – Vancomycin monograph (2020) Comment: TDM required. Seek AMS/ Paediatric pharmacist advice. |
