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Octreotide

Presentation

  • 50 micrograms/mL ampoules
  • 100 micrograms/mL ampoules
  • 500 micrograms/mL ampoules

*KEEP REFRIGERATED*

Role

Treatment of hypoglycaemia (BSL< 4.0 mmol/L) due to sulfonylurea overdose; following the initial correction with glucose. Commencing octreotide should prevent the need for an ongoing glucose infusion.

Octreotide

Dose

  • 50 micrograms (child: 2 micrograms/kg) q8h SC for at least 24 hours.
  • 50 micrograms (child: 2 micrograms/kg) IV load, followed by 25 micrograms/hour (child: 1microgram/kg/hour) infusion for at least 24hours.

Stocking recommendations

Tertiary centre Regional centre Rural centre Remote centre

Readily available for other indications

Readily available for other indications Readily available for other indications 0 ampoules

Rationale

Octreotide is usually readily available in hospitals for other indications. Sufficient stock to treat a patient for at least 24 hours is recommended in rural centres.

Disclaimer

Fact sheet developed by Queensland Poisons Information Centre, Updated: July 2020.

This fact sheet is about the use of these antidotes in Australia, and may not apply to other countries. Children’s Health Queensland Hospital and Health Service cannot be held responsible for the accuracy of information, omissions of information, or any actions that may be taken as a consequence of reading this fact sheet.

CHQ